When Standard Treatment Isn’t Enough: Complex Schizophrenia Cases and Clinical Decision-Making

Not all patients with schizophrenia respond predictably to first-line antipsychotic therapy. This panel discussion uses challenging clinical cases to examine treatment resistance, persistent positive symptoms, comorbid mood instability, and functional decline. Faculty will discuss sequencing strategies, clozapine timing, augmentation options, and managing adverse effects such as metabolic burden and sedation. Attendees will gain step-by-step guidance on refining treatment plans when conventional approaches fail to produce meaningful recovery.