James F. Benenati, M.D., FSIR, is a practicing Interventional Radiologist at the Miami Cardiac & Vascular Institute at Baptist Hospital in Miami, Florida where he has practiced for 31 years. He serves as the Chief Medical Officer of Penumbra Inc.

He is the former Medical Director of the Noninvasive Vascular Laboratory and Fellowship Program Director at the Miami Cardiac & Vascular Institute.
He is a Clinical Professor of Radiology at Florida International University College of Medicine and Collaborative Professor of Radiology at the University of South Florida College of Medicine. He is past President of SIR. He served as President of the Vascular Division for the Intersocietal Accreditation Committee and served for over a decade on their board. He served as the annual meeting chairman for SIR in 2005. He was the recipient of the SIR Charles T. Dotter Award in 2014 and the SIR Gold medal recipient in 2020.

He has participated in numerous clinical research projects and national trials. His interest include peripheral arterial disease, abdominal aortic aneurysm and management of pulmonary embolism. He has authored more than 100 scientific publications