Faculty

Sarah Rutherford

MD
Associate Professor of Medicine (Clinical)
NYU Langone Health

Dr. Sarah Rutherford is an Associate Professor of Medicine (Clinical) in the Division of Hematology/Oncology at NYU Langone Health. She is a graduate of the University of Virginia School of Medicine. She completed Internship and Residency in Internal Medicine at Thomas Jefferson University Hospital in Philadelphia and Fellowship in Hematology/Oncology at New York-Presbyterian Hospital/Weill Cornell Medical College.

Dr. Rutherford has clinical expertise in lymphoma. Her research focuses on novel therapeutic strategies in B-cell and Hodgkin lymphomas. She has received honors from Weill Cornell Medical College and the American Society of Hematology, and support from the New York State Empire Clinical Research Investigator Program, the Lymphoma Research Foundation, the National Institutes of Health Clinical Loan Repayment Program, and the Alliance for Clinical Trials Foundation. She has experience in caring for patients with a variety of lymphomas and hematologic disorders including Hodgkin lymphoma, chronic lymphocytic leukemia, diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, marginal zone lymphoma, and peripheral T-cell lymphoma.

2026 Sessions

The Post–R-CHOP Era: Novel Therapies and Evolving Standards in Aggressive Lymphoma

The treatment landscape for aggressive B-cell lymphomas is rapidly evolving beyond the longstanding R-CHOP paradigm. Recent data f have established polatuzumab vedotin plus R-CHP as a frontline standard for selected high-risk patients, while novel immunotherapy-based combinations such as tafasitamab/lenalidomide plus R-CHOP and epcoritamab plus R-CHOP are demonstrating encouraging efficacy in earlier treatment settings. In relapsed or refractory disease, CAR T-cell therapy continues to redefine second-line management, and CD20×CD3 bispecific antibodies are expanding effective off-the-shelf treatment options. This session , led by Dr. Sarah Rutherford, will review the latest evidence, emerging standards of care, and practical strategies for integrating these advances into contemporary clinical practice.

Speaker

Wednesday, October 14 10:05–10:25 AM
Room Broadway South
Faculty

Sarah Rutherford

MD
Associate Professor of Medicine (Clinical)
NYU Langone Health

Dr. Sarah Rutherford is an Associate Professor of Medicine (Clinical) in the Division of Hematology/Oncology at NYU Langone Health. She is a graduate of the University of Virginia School of Medicine. She completed Internship and Residency in Internal Medicine at Thomas Jefferson University Hospital in Philadelphia and Fellowship in Hematology/Oncology at New York-Presbyterian Hospital/Weill Cornell Medical College.

Dr. Rutherford has clinical expertise in lymphoma. Her research focuses on novel therapeutic strategies in B-cell and Hodgkin lymphomas. She has received honors from Weill Cornell Medical College and the American Society of Hematology, and support from the New York State Empire Clinical Research Investigator Program, the Lymphoma Research Foundation, the National Institutes of Health Clinical Loan Repayment Program, and the Alliance for Clinical Trials Foundation. She has experience in caring for patients with a variety of lymphomas and hematologic disorders including Hodgkin lymphoma, chronic lymphocytic leukemia, diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, marginal zone lymphoma, and peripheral T-cell lymphoma.

Q&A

Moderator

Panelist

Wednesday, October 14 11:10–11:45 AM
Room Broadway South
Faculty

John Leonard

MD
Laura and Isaac Perlmutter Professor of Hematology and Medical Oncology
NYU Langone Health and NYU Grossman School of Medicine.

John P. Leonard, M.D., is the Laura and Isaac Perlmutter Professor of Hematology and Medical Oncology, Chief of the Division of Hematology and Medical Oncology and Director, Center for Blood Cancers at Perlmutter Cancer Center at NYU Langone Health and NYU Grossman School of Medicine.
An expert in hematology and oncology, Dr. Leonard is Chair of the Lymphoma Committee of the Alliance for Clinical Trials in Oncology (formerly CALGB, ACOSOG and NCCTG), a multicenter cooperative group and key component of the National Cancer Institute’s National Clinical Trials Network. Dr. Leonard has been an elected member of the American Board of Internal Medicine Hematology subspecialty board, and he has also been elected to membership in the American Society of Clinical Investigation. He has served as Chair of the Scientific Advisory Board and Board Member of the Lymphoma Research Foundation and Board Member of the Leukemia and Lymphoma Society/New York City Chapter.
Dr. Leonard performed his undergraduate work at Johns Hopkins University and received his medical degree at the University of Virginia in Charlottesville, VA. He completed his residency in medicine at the New York Hospital - Cornell Medical Center and Memorial Sloan-Kettering Cancer Center in New York, NY. He completed a fellowship in hematology and oncology at Cornell, and served as the chief medical resident at the New York Hospital - Cornell Medical Center.

Faculty

Nilanjan Ghosh

MD, PhD, FACP
Chief Division of Hematology, Professor of Cancer Medicine
Atrium Health Levine Cancer Institute, Wake Forest Uni School of Medicine

Dr. Ghosh is the Kerry and Simone Vickar Family Foundation Endowed Chair and Professor of Cancer Medicine at Wake Forest University School of Medicine in Charlotte and Chief, Division of Hematology at Atrium Health Levine Cancer Instiute. He also leads the Lymphoam progam. He specializes in lymphoma and chronic lymphocytic leukemia.
Dr. Ghosh’s research interests include CAR T-cell therapy, bispecific antibodies, and overcoming disparities in healthcare. He has published research manuscripts in prestigious journals. He serves as a principal investigator on numerous innovative clinical trials.
Dr. Ghosh has received awards from the American Society of Clinical Oncology (ASCO) and the Leukemia Lymphoma Society (LLS) now rebranded as Blood Cancer United. He has been named a Charlotte magazine Top Doctor and is a Castle Connolly Top Doctor.

Faculty

Sarah Rutherford

MD
Associate Professor of Medicine (Clinical)
NYU Langone Health

Dr. Sarah Rutherford is an Associate Professor of Medicine (Clinical) in the Division of Hematology/Oncology at NYU Langone Health. She is a graduate of the University of Virginia School of Medicine. She completed Internship and Residency in Internal Medicine at Thomas Jefferson University Hospital in Philadelphia and Fellowship in Hematology/Oncology at New York-Presbyterian Hospital/Weill Cornell Medical College.

Dr. Rutherford has clinical expertise in lymphoma. Her research focuses on novel therapeutic strategies in B-cell and Hodgkin lymphomas. She has received honors from Weill Cornell Medical College and the American Society of Hematology, and support from the New York State Empire Clinical Research Investigator Program, the Lymphoma Research Foundation, the National Institutes of Health Clinical Loan Repayment Program, and the Alliance for Clinical Trials Foundation. She has experience in caring for patients with a variety of lymphomas and hematologic disorders including Hodgkin lymphoma, chronic lymphocytic leukemia, diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, marginal zone lymphoma, and peripheral T-cell lymphoma.

Faculty

Sonali Smith

MD, FASCO
Elwood V. Jensen Professor of Medicine
Chief, Section of Hematology/Oncology
Co-Leader, Cancer Service Line
Co-Director, Lymphoma Program
The University of Chicago

Dr. Sonali M. Smith is the Elwood V. Jensen Professor of Medicine, Section Chief of Hematology/Oncology and Co-Leader of the Cancer Service Line, at the University of Chicago. She is a clinical investigator in lymphoma and a clinical expert in mature lymphoid malignancies including Hodgkin and non-Hodgkin lymphomas. A faculty member since 2001, she has written or co-written dozens of clinical trials, and has participated in many more with key input in the clinical design, determination of endpoints, and analysis. She has nearly 200 publications in peer-reviewed journals. She is particularly interested in targeted agents and pathway inhibitors and has first and senior author publications through cooperative group trials and investigator-initiated trials. A significant portion of her research has focused on prognosis and the ability to deliver individualized therapy.

Dr. Smith serves in the Medical Oncologist seat on the ASCO Society Board of Directors for the 2026-2027 term. She chaired the ASCO Cancer Communications Committee, the Professional Development Committee, and the Scientific Committee Program. Dr. Smith is a past recipient of the ASCO Excellence in Teaching award. She has had leadership roles in other oncology groups such as the Vice-Chair of the SWOG Lymphoma Committee for a decade before becoming the Chair in 2026, past-Chair of the LRF Scientific Advisory Board, co-chair of the 2022 AACR Advances in Malignant Lymphoma, and co-chair of the ASH Meeting on Hematologic Malignancies. Dr. Smith is one of the founding members and Steering Committee members of the international Women in Lymphoma group.

Q&A

Moderator

Panelist

Wednesday, October 14 5:35–5:50 PM
Room Broadway South
Faculty

Sarah Rutherford

MD
Associate Professor of Medicine (Clinical)
NYU Langone Health

Dr. Sarah Rutherford is an Associate Professor of Medicine (Clinical) in the Division of Hematology/Oncology at NYU Langone Health. She is a graduate of the University of Virginia School of Medicine. She completed Internship and Residency in Internal Medicine at Thomas Jefferson University Hospital in Philadelphia and Fellowship in Hematology/Oncology at New York-Presbyterian Hospital/Weill Cornell Medical College.

Dr. Rutherford has clinical expertise in lymphoma. Her research focuses on novel therapeutic strategies in B-cell and Hodgkin lymphomas. She has received honors from Weill Cornell Medical College and the American Society of Hematology, and support from the New York State Empire Clinical Research Investigator Program, the Lymphoma Research Foundation, the National Institutes of Health Clinical Loan Repayment Program, and the Alliance for Clinical Trials Foundation. She has experience in caring for patients with a variety of lymphomas and hematologic disorders including Hodgkin lymphoma, chronic lymphocytic leukemia, diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, marginal zone lymphoma, and peripheral T-cell lymphoma.

Faculty

Catherine Diefenbach

MD
Associate Professor of Medicine
Perlmutter Cancer Center, NYU Grossman School of Medicine, NYU Langone Health

I am a Professor in the Division of Hematology and Medical Oncology in the NYU Perlmutter Cancer Center (PCC) at NYU Langone Health, the Clinical Director of Lymphoma and the Translational Director of Hematology. My scientific research focuses on the relationship between systemic immunity, tumor microenvironment, and lymphoid malignancies. I lead a multi-center investigation into the role of the microbiome in aggressive lymphoma and the development of novel CAR T cell constructs , and collaborate in team science with basic scientists in the development of novel immune based therapies, and biomarkers of lymphoma response. I have been among the pioneers of integration of checkpoint inhibitor therapy into the management of Hodgkin lymphoma (HL) developing and led a national ETCTN supported clinical trial in this space. I have also played a key role in the development of novel immune related biomarkers in HL, and serve on national committees leading efforts to improve the next generation of HL therapies. I have contributed to the development of antibody drug conjugates (ADC) and bispecific antibodies in DLBCL and FL , and led national and international studies for relapsed FL and DLBCL. I have successfully obtained external peer-reviewed funding for my translational research from: the Lymphoma Research Foundation, the American Cancer Society, the Leukemia Lymphoma Foundation (LLS) and the National Cancer institute (NCI).

Faculty

Alison Moskowitz

MD
Associate Attending
Memorial Sloan Kettering Cancer Center

Dr. Alison Moskowitz is an Associate Attending within the Lymphoma service at Memorial Sloan Kettering Cancer Center. She earned her medical degree at Albert Einstein College of Medicine, completed an internship and residency in internal medicine at Columbia University Medical Center, and completed fellowship in medical oncology at Memorial Sloan Kettering Cancer Center.
Dr. Moskowitz’s research is dedicated to developing new treatment strategies for T-cell lymphoma and relapsed/refractory Hodgkin lymphoma. Her research program in Hodgkin lymphoma focuses on developing novel treatment approaches for patients with relapsed or refractory disease and identifying factors predictive of response to therapy and overall outcomes. The aim of this work is to ultimately develop individualized therapy for patients with Hodgkin lymphoma that optimizes cure and limits long-term toxicity.
For T-cell lymphoma, she aims to develop new agents through clinical trials that incorporate strong correlative studies aimed at identifying markers of sensitivity and resistance. These studies will allow us to design personalized treatment approaches, predict optimal combination strategies, and ultimately improve prognosis by rationally designing regimens that target the diverse T-cell lymphoma entities.

Faculty

Jia Ruan

MD, PhD
Professor of Clinical Medicine
Weill Cornell Medicine

Dr. Ruan is a Professor of Clinical Medicine in the Division of Hematology and Medical Oncology at Weill Cornell Medicine and New York Presbyterian Hospital. She specializes in the treatment of lymphoma, and leads clinical research trials in mantle cell lymphoma and peripheral T-cell lymphoma at Weill Cornell Medicine. Dr. Ruan received comprehensive training in medicine and immunology leading to combined MD-PhD degrees from the Tri-Institutional Medical Scientist Training Program of Cornell University, the Rockefeller University and Sloan-Kettering Cancer Institute. She completed residency and fellowship in hematology/oncology at the Stanford University Medical Center and New York Presbyterian Hospital before joining faculty at Weill Cornell Medicine. Dr. Ruan’s research expertise focuses on novel therapeutics targeting tumor microenvironment and tumor immunology in both B-cell and T-cell non-Hodgkin lymphomas. She contributes to the American Society of Hematology as an annual meeting abstract reviewer/coordinating reviewer, Highlights of ASH speaker and Education Session Chair. She has been a faculty for the ASH Clinical Research Training Institute since 2021. She serves on the lymphoma committee of the cooperative intergroup ALLIANCE, and the Lymphoma Research Foundation MCL Research Consortium. She also co-leads the T-cell lymphoma Working Group for the LEO Consortium. Her research efforts were recognized and supported by funding from the LRF, the ASCO Foundation, the LLS, and the NIH. Dr. Ruan has published articles in leading research journals including the Journal of Experimental Medicine, PNAS, Blood, Annals of Oncology, Cancer, the Journal of Clinical Oncology, Lancet Oncology and the New England Journal of Medicine.

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