Ketamine in 2025: Myths, Breakthroughs, and Evolving Evidence

Ketamine has evolved far beyond its traditional role as a dissociative anesthetic, emerging as one of the most versatile agents in both critical care and mental health treatment. Ketamine in 2025: Myths, Breakthroughs, and Evolving Evidence examines the latest clinical applications, controversies, and scientific advances shaping its use across prehospital, emergency, and critical care environments. This course challenges outdated perceptions while exploring evidence-based indications for ketamine in analgesia, sedation, rapid sequence intubation, refractory status asthmaticus, traumatic brain injury, and treatment-resistant depression. Learners will analyze pharmacologic mechanisms, safety data, and evolving research that supports ketamine’s expanding role in modern medicine. By separating myth from science, this session empowers clinicians to apply current best practices and ethical considerations in ketamine administration for both adult and pediatric populations.