Elizabeth A. Spencer, MD, MS is a pediatric gastroenterologist and Associate Professor of Pediatrics at the Icahn School of Medicine at Mount Sinai, specializing in IBD in children and adolescents with a focus on early detection, precision care, and noninvasive monitoring.
Dr. Spencer directs the Pediatric IBD Translational Medicine Program and co-directs the Mount Sinai IBD-Dermatology Clinic, a multidisciplinary program for patients with overlapping IBD and dermatologic immune-mediated diseases. She also co-founded and co-directs the Mount Sinai IBD Prevention Program, which provides proactive care to children and adults at high risk of developing IBD.
Her research leverages large-scale biorepositories and real-world data to evaluate treatment effectiveness and safety in pediatric IBD and to define the preclinical phase of disease. She is Principal Investigator of an NIH K23 award studying multiplex IBD families and an investigator on PCORI- and Helmsley-funded studies, including as Site Principal Investigator and Northeast Region Lead for COMPARE. A certified guideline methodologist, she contributes to ACG and NASPGHAN guideline development and leads national efforts to standardize intestinal ultrasound training and care pathways.
Dr. Spencer received her MD with honors (AOA, GHHS) from Eastern Virginia Medical School and completed pediatric residency at UCLA, followed by pediatric gastroenterology and advanced IBD fellowships and a master's in clinical research at Mount Sinai. Recent honors include consecutive Cullman Family Awards for physician communication and two Team Science Awards. An IBD patient herself, diagnosed at 15, she is deeply committed to advancing pediatric-centered innovation in IBD prevention, diagnosis, and treatment.