Elizabeth Spencer

MD, MS
Assistant Professor of Pediatric Gastroenterology
Associate Program Director, Pediatric Research Residency
Director, Pediatric IBD Translational Research Program
Co-Director, IBD-Dermatology Multidisciplinary Clinic
Co-Director, IBD Prevention Clinic
Mount Sinai, Icahn School of Medicine, New York, NY

Elizabeth A. Spencer, MD, MS is a pediatric gastroenterologist and Assistant Professor of Pediatrics at the Icahn School of Medicine at Mount Sinai. She specializes in inflammatory bowel diseases (IBD) in children and adolescents, with a focus on early detection, precision care, and noninvasive disease monitoring.

Dr. Spencer is the Director of the Pediatric Translational Medicine, Interim Director of Intestinal Ultrasound, and Co-Director of the Mount Sinai IBD-Dermatology Clinic, an innovative multidisciplinary program for children with overlapping gastrointestinal and dermatologic immune-mediated diseases. She also founded and directs the first-ever IBD Prevention Program, which provides proactive care for children and adults at high risk of developing IBD.

Her research leverages large-scale biorepositories and real-world data to evaluate treatment effectiveness and safety in pediatric IBD. She serves as an investigator on PCORI- and NIH-funded studies, including COMPARE, and leads national efforts to standardize intestinal ultrasound training and care pathways. She contributes to international pediatric IBD guideline development.

Dr. Spencer received her MD with honors (AOA, GHHS) from Eastern Virginia Medical School and completed her pediatric residency at UCLA, followed by pediatric gastroenterology and advanced IBD fellowships and a master’s degree in clinical research at Mount Sinai, Icahn School of Medicine. In 2025 alone, she has received awards for her collaborative research, her communication with patients, and her academic rigor. A pediatric IBD patient herself, she is deeply committed to advancing child-centered innovation in IBD prevention, diagnosis, and treatment.

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