Platinum Sensitivity Still Rules: Sequencing, Not Target Expression, Should Drive Decisions

This session will examine treatment selection in recurrent ovarian cancer in the era of antibody-drug conjugates (ADCs). Faculty will compare biomarker-driven use of agents such as mirvetuximab with traditional platinum-based sequencing strategies, reviewing clinical evidence, resistance patterns, and practical considerations. Participants will gain insight into how emerging therapies may reshape decision-making. This discussion will emphasize the continued importance of platinum sensitivity in guiding treatment sequencing. Faculty will review evidence supporting established platinum-based approaches and argue that clinical context and sequencing strategy remain more impactful than target expression alone, with attention to durability, toxicity, and real-world applicability.