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Faculty

Marina Frimer

MD
Associate Chief, Research and Academic Development
Northwell Health

Dr. Marina Frimer, a distinguished Gynecologic Oncologist, is currently the Vice Chair of Research and Academic Development at Northwell Health’s Department of Obstetrics and Gynecology. At Northwell Cancer Institute, Dr. Frimer is spearheading the development of a robust clinical and translational research program. Dr. Frimer is also the Director of Clinical Cancer Research at the Northwell Queens Cancer Center. Her translational work focuses on rare uterine cancers and cancer genomics, with collaborations with Cold Spring Harbor Laboratory. Her innovative translational research involves developing pre-clinical endometrial cancer models, including the cultivation of organoids to explore high grade uterine cancers and therapeutic options. Dr. Frimer has authored multiple publications and secured several grants to support her research initiatives. Notable projects include examining the mechanisms behind endometrial cancer disparities in African American populations and creating multi-omics maps of the human endometrium across diverse ancestries. Additionally, she is dedicated to building trust in clinical trials, partnering with the Hispanic Counseling Center to engage underrepresented communities. Dr. Frimer maintains an active clinical practice seeing patients with all gynecologic malignancies.

2026 Sessions

General Session

Recurrent Ovarian Cancer in the ADC Era: Mirvetuximab and Emerging ADCs Should Define Treatment Selection by Biomarker vs Platinum Sensitivity Still Rules: Sequencing, Not Target Expression, Should Drive Decisions

This session will examine treatment selection in recurrent ovarian cancer in the era of antibody-drug conjugates (ADCs). Faculty will compare biomarker-driven use of agents such as...

  • Moderator
    • Kathleen Moore, MD, MS
  • Presenter
    • Marina Frimer, MD
    • Rebecca Porter, MD, PhD
Gynecological Cancers

Mirvetuximab and Emerging ADCs Should Define Treatment Selection by Biomarker

This session will examine treatment selection in recurrent ovarian cancer in the era of antibody-drug conjugates (ADCs). Faculty will compare biomarker-driven use of agents such as mirvetuximab with traditional platinum-based sequencing strategies, reviewing clinical evidence, resistance patterns, and practical considerations. Participants will gain insight into how emerging therapies may reshape decision-making.

This discussion will focus on the growing role of ADCs, including mirvetuximab, as biomarker-selected therapies. Faculty will review clinical trial data supporting improved outcomes in target-expressing populations and discuss how biomarker testing can guide treatment selection, improve precision, and potentially shift sequencing paradigms.

Debate Speaker

Sunday, September 27 1:30–1:50 PM
Gynecological Cancers
Faculty

Rebecca Porter

MD, PhD
Assistant Professor
Dana-Farber Cancer Institute

Dr. Rebecca Porter, MD, PhD is a Medical Oncologist in the Division of Gynecologic Oncology at Dana Farber Cancer Institute and an Assistant Professor of Medicine at Harvard Medical School. She also serves as the Director of Immunotherapy Research for the Division of Gynecologic Oncology, and her clinical and research efforts are centered on developing and translating novel immunotherapy strategies, including adoptive cell therapies, to patients with gynecologic cancers as well as performing biomarker studies to identify mediators of response and resistance to therapy. Dr. Porter maintains an active clinical practice seeing patients with ovarian, endometrial, cervical, vaginal and vulvar cancers.

Platinum Sensitivity Still Rules: Sequencing, Not Target Expression, Should Drive Decisions

This session will examine treatment selection in recurrent ovarian cancer in the era of antibody-drug conjugates (ADCs). Faculty will compare biomarker-driven use of agents such as mirvetuximab with traditional platinum-based sequencing strategies, reviewing clinical evidence, resistance patterns, and practical considerations. Participants will gain insight into how emerging therapies may reshape decision-making.

This discussion will emphasize the continued importance of platinum sensitivity in guiding treatment sequencing. Faculty will review evidence supporting established platinum-based approaches and argue that clinical context and sequencing strategy remain more impactful than target expression alone, with attention to durability, toxicity, and real-world applicability.

Debate Speaker

Sunday, September 27 1:50–2:10 PM
Gynecological Cancers
Faculty

Marina Frimer

MD
Associate Chief, Research and Academic Development
Northwell Health

Dr. Marina Frimer, a distinguished Gynecologic Oncologist, is currently the Vice Chair of Research and Academic Development at Northwell Health’s Department of Obstetrics and Gynecology. At Northwell Cancer Institute, Dr. Frimer is spearheading the development of a robust clinical and translational research program. Dr. Frimer is also the Director of Clinical Cancer Research at the Northwell Queens Cancer Center. Her translational work focuses on rare uterine cancers and cancer genomics, with collaborations with Cold Spring Harbor Laboratory. Her innovative translational research involves developing pre-clinical endometrial cancer models, including the cultivation of organoids to explore high grade uterine cancers and therapeutic options. Dr. Frimer has authored multiple publications and secured several grants to support her research initiatives. Notable projects include examining the mechanisms behind endometrial cancer disparities in African American populations and creating multi-omics maps of the human endometrium across diverse ancestries. Additionally, she is dedicated to building trust in clinical trials, partnering with the Hispanic Counseling Center to engage underrepresented communities. Dr. Frimer maintains an active clinical practice seeing patients with all gynecologic malignancies.

Platinum Sensitivity Still Rules: Sequencing, Not Target Expression, Should Drive Decisions

This session will examine treatment selection in recurrent ovarian cancer in the era of antibody-drug conjugates (ADCs). Faculty will compare biomarker-driven use of agents such as mirvetuximab with traditional platinum-based sequencing strategies, reviewing clinical evidence, resistance patterns, and practical considerations. Participants will gain insight into how emerging therapies may reshape decision-making.

This discussion will emphasize the continued importance of platinum sensitivity in guiding treatment sequencing. Faculty will review evidence supporting established platinum-based approaches and argue that clinical context and sequencing strategy remain more impactful than target expression alone, with attention to durability, toxicity, and real-world applicability.

Debate Speaker

Sunday, September 27 1:50–2:10 PM
Gynecological Cancers
Faculty

Marina Frimer

MD
Associate Chief, Research and Academic Development
Northwell Health

Dr. Marina Frimer, a distinguished Gynecologic Oncologist, is currently the Vice Chair of Research and Academic Development at Northwell Health’s Department of Obstetrics and Gynecology. At Northwell Cancer Institute, Dr. Frimer is spearheading the development of a robust clinical and translational research program. Dr. Frimer is also the Director of Clinical Cancer Research at the Northwell Queens Cancer Center. Her translational work focuses on rare uterine cancers and cancer genomics, with collaborations with Cold Spring Harbor Laboratory. Her innovative translational research involves developing pre-clinical endometrial cancer models, including the cultivation of organoids to explore high grade uterine cancers and therapeutic options. Dr. Frimer has authored multiple publications and secured several grants to support her research initiatives. Notable projects include examining the mechanisms behind endometrial cancer disparities in African American populations and creating multi-omics maps of the human endometrium across diverse ancestries. Additionally, she is dedicated to building trust in clinical trials, partnering with the Hispanic Counseling Center to engage underrepresented communities. Dr. Frimer maintains an active clinical practice seeing patients with all gynecologic malignancies.
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