WHS Session D: Cross-Talk at the Wound Interface: Microbiome and Immune Dynamics in Infection

This session delves into the dynamic cross-talk between microbes and the immune system that determines whether wounds heal or persist in inflammation. Presentations will highlight how shifts in the wound microbiome reshape repair processes and how cytotoxic and regulatory immune cell responses can both defend against and drive tissue damage. Together, these talks by this collaborative team uncover emerging principles of immune–microbial balance with broad implications for infection control and chronic wound management.

Microbial-Host Interactions and Impaired Wound Healing
Elizabeth A. Grice, PhD

The Complex Role of CD8+ T Cells in Wound Healing and Chronic Cutaneous Leishmaniasis
Phillip Scott, PhD