FIBROSIS AND SCARRING (L3)

ROOM: Fort Worth 6
MODERATORS: ANIE PHILIP, PHD; SWATHI BALAJI, MD

L3.01. Radiation Triggers A Clinically Relevant Pro-Fibrotic p53-Mediated DNA Damage Response In An Ex Vivo Human Skin Model

Caroline Dodson1,3; Sophie M. Bilik1; Gabrielle DiBartolomeo1; Hannah Pachalis1; Seth Thaller2; Irena Pastar1; Marjana Tomic-Canic1,3; Anthony Griswold3; Rivka C. Stone1,3
1Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, United States; 2Plastic, Aesthetic and Reconstructive Surgery, University of Miami Miller School of Medicine, Miami, FL, United States; 3Human Genetics and Genomics, University of Miami Miller School of Medicine, Miami, FL, United States

L3.02. Diabetes Increases Fibrosis in Response to Liver Injury in Mice

Syed Maisam Jafri; Maria Gracia Mora Pinos; Katharina S. Fischer; Abdelrahman M. Alsharif; Fidel Saenz; Hudson C. Kussie; Dharshan Sivaraj; Andrew Hostler; William Hahn; Filiberto Quintero; Maia Granoski; Eamonn McKenna; Kenneth W. Liechty
Surgery, University of Arizona, Tucson, AZ, United States

L3.03. Expression of MARCKSL1 in Dendritic Cells Modulates Fibroblast Differentiation and Promotes Scar Formation

Kento Takaya; Yukari Nakajima; Noriko Aramaki-Hattori; Keisuke Okabe; Shigeki Sakai; Kazuo Kishi
Plastic and Reconstructive Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

L3.04. Degradation of Versican in Keloids

Noriko Aramaki; Keisuke Okabe; Kazuo Kishi
Department of Plastic and Reconstructive Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

L3.05. PKM2 and HSP27 Phosphorylation in Response to Mechanical Signaling Regulate Energy Metabolism and Fibrotic Responses in Dermal Fibroblasts
Jaime Tellez; Mary Elizabeth Guerra; Pranav Bommekal; Casey Baxter; Nabila N. Anika; Navya Nanda; Sonya S. Keswani; Zara Chandrashekar; Hui Li; Ling Yu; Sundeep Keswani; Swathi Balaji
Pediatric Surgery, Baylor College of Medicine, Houston, TX, United States

L3.06. Role of IL-2 on Tr1 Activation and Fibroblast Function in Dermal Wound Healing

Efua H. Bolouvi; Maria Emilia Mora; Anisha Apte; Jimena Canchis Angulo; Jacob Diermayr; Yona Kleinerman; Stacy Skopp; Alyssa San Agustin; Kenneth Casey Baxter1; Navya Nanda1; Sonya Keswani1; Anjali Degala1; Pranav Bommekal1; Jaime Tellez1; Hui Li1; Ling Yu1; Mary Elizabeth Guerra1; Paul Bollyky2; Sundeep G. Keswani1; Swathi Balaji1
1Pediatric Surgery, Baylor College of Medicine, Houston, TX, United States; 2Immunology, Stanford University School of Medicine, Palo Alto, CO, United States